The César A. Mena Collection contains the documentation and research notes used by Dr. César A. Mena Serra to write his work Historia de la medicina en Cuba (History of Medicine in Cuba), which was published in two volumes by Ediciones Universal in Miami, Florida. The first volume, Hospitales y centros benéficos en Cuba colonial (Hospitals and charity centers in colonial Cuba), was published in 1992, and the second volume, Ejercicios y enseñanzas de las ciencias médicas en la época colonial (Exercises and teachings of the medical sciences in colonial Cuba), was published in 1993. Dr. Armando F. Cobelo was co-author of these works.

This collection also contains the galley proofs and illustrations of volumes one and two; the original manuscript of volume two; and an invitation to the presentation of the volume one in March 1992.