Thomas Jefferson (1742-1826) was the primary author of the Declaration of Independence (1776), Governor of Virginia (1779-1781), the first Secretary of State (1790-1793), second Vice-President of the United Sates (1797-1801), the third President of the United States (1801–1809), the founder of the University of Virginia (1819), and one of the most influential Founding Fathers.

The Thomas Jefferson collection includes four letters by Thomas Jefferson, three official documents, an entry of merchandise, a biography, and twenty-six printed portraits.