The Isaac Bashevis Singer Collection consists predominantly of correspondence written to Singer during the years 1978 to 1982. The correspondence is divided topically into the following categories: agent correspondence, autograph and photograph requests, fan mail, financial papers, Hebrew and Yiddish correspondence, legal affairs, miscellaneous, "new writer" requests (letters from authors asking Singer to read their work), personal, protocol, publicity, publisher and producer correspondence, requests for information, requests for money, and requests for interviews or speaking engagements.

Also included are manuscripts by Singer, periodicals, brochures, photocopies, and clippings with content from or about Singer, and writings by other authors.